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NORD posts this report because limited information is available about this condition and it may be underdiagnosed

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The results were impressive, with a significant number of people losing 20% of their body weight

Some medications, such as tirzepatide, also activate another hormone pathway called GIP (glucose-dependent insulinotropic polypeptide), which may further improve blood sugar control and contribute to greater weight loss in some people

Injecting a solo dose of MTX (20 mg/kg) caused a non-significant 66% and 54% elevation in total and free carnitine, respectively, compared with the control